Equine lutropin and chorionic gonadotropin bear oligosaccharides terminating with SO4-4-GalNAc and Sia alpha 2,3Gal, respectively.
نویسندگان
چکیده
منابع مشابه
Molecular basis of recognition by the glycoprotein hormone-specific N-acetylgalactosamine-transferase.
Lutropin (LH) bears asparagine-linked oligosaccharides terminating with the unique sequence SO4-4GalNAc beta 1-4GlcNAc beta 1-2Man alpha, whereas follitropin (FSH) bears oligosaccharides terminating predominantly with the sequence Sia alpha-Gal beta 1-4GlcNAc beta 1-2Man alpha, where Sia is sialic acid. We previously identified a glycoprotein-hormone-specific N-acetylgalactosamine-transferase (...
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The beta subunits of equine lutropin and equine chorionic gonadotropin were incubated in 0.013 N HCl for 30 min at 110 degrees C and separated into two fragments by reverse-phase high performance liquid chromatography. The amino acid and carbohydrate compositions of both fragments from each subunit were analyzed. The results demonstrated that equine lutropin-beta has a glycosylated COOH-termina...
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We have determined that 280% of the Asn-linked oligosaccharides on the glycosylated form of mouse adrenocorticotropin (15-kDa adrenocorticotropin (ACTH)) bear one or more branches terminating with the sequence S04-4GalNAc/31,4GlcNAc~1, 2Mana (S4GGnM). Proopiomelanocortin (POMC), the precursor of ACTH, is the first example of a glycoprotein that is not a member of the glycoprotein hormone f...
متن کاملEquine Chorionic Gonadotropin in African N’dama Cattle
Given its rustic nature, its butchery quality and its trypanotolerance, the N’Dama breed represents a significant potential for developing African cattle breeding [6]. To date, its zootechnical performance and reproductive characteristics have been the subject of relatively little work. The use of selection programmes and artificial insemination are highly significant challenges for developing ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1993
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)54004-7